| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e3e4b073de9f1805c5e11132968781d3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f4dc8fa9f0dcfd25d674614a9a6d35f1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bfc17e2391c038b9a0678e26d2914ff9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad438515d9a023baf4e5fe36970e7448 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate |
2010-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2013-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d0d730525e284c4b6ae9db367fa971f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88025d7e64a8be0765f0d1eb87830948
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc9e1884414242c8f7ac82054c47d154 |
| publicationDate |
2013-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8497371-B2 |
| titleOfInvention |
Pipemidic acid derivative autotaxin inhibitors |
| abstract |
Novel and optimized classes of pipemidic acid derivative compounds that exhibit effective inhibition of autotaxin enzymes are provided. Such classes of compounds exhibit exhibit reactivity with autotaxin to ultimately reduce the size of the reactive sites thereon to prevent conversion of lysophosphatidyl choline to lysophophatidic acid. Furthermore, such compounds can be incorporated within delivery forms for human ingestion. As such, these compounds accord an excellent manner of potentially reducing generation of certain cancers attributable to the presence of naturally occurring autotaxin within the human body. Methods of inactivating autotaxin to certain degrees therewith such compounds are encompassed within invention as well. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10688081-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10632104-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11779568-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9999615-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9850203-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9951026-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9926318-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9714240-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10520507-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9051320-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9334261-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9468628-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11344533-B2 |
| priorityDate |
2009-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |