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filingDate 2005-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2013-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8496833-B2
titleOfInvention Leukocyte removal method
abstract A method of removing leukocytes that through reducing of clogging of a leukocyte removing filter element by blood cell components and plasma proteins being a problem encountered at the time of removing leukocytes from blood, shortens the filtration time at refrigerated filtration and exhibits high leukocyte removing performance at room temperature filtration. There is provided a method of removing leukocytes including filtering blood containing leukocytes through a leukocyte removing filter apparatus having multiple fibrous filter elements with different average fiber diameters to thereby remove leukocytes from the blood, characterized in that use is made of a leukocyte removing filter apparatus wherein the multiple fibrous filter elements include at least leukocyte removing filter element (A) of 2.0 to <4.0 μm average fiber diameter and leukocyte removing filter element (B) of 0.7 to 1.2 μm average fiber diameter and wherein the filter element (B) is disposed downstream of the filter element (A), the leukocyte removing filter element (B) having an average fiber diameter of >17.5% to <50% of that of the filter element (A).
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