Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_709b4a26ef028713f9b302509eb824d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad7055bbe10cff6cc30f295840ca3553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4883ee33c29216d99e5031987c31cf1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91097 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-143333 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-48 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2010-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2013-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0be6b7fe37309343b0add88d7ea06601 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25c360eb4a1e04640e46a200c2ee1ee5 |
publicationDate |
2013-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8476023-B2 |
titleOfInvention |
Methods relating to aromatase inhibitor pharmacogenetics |
abstract |
Methods for aiding in determining therapeutic efficacy of an aromatase inhibitor in a subject are provided according to embodiments of the present invention which include detecting expression and/or function of at least one UDP-glucuronosyltransferase having activity to modify at least one aromatase inhibitor and/or metabolite of the aromatase inhibitor by glucuronidation, wherein detection of expression and/or function of the UDP-glucuronosyltransferase is correlated with therapeutic efficacy of the aromatase inhibitor in the subject. Detection of UDP-glucuronosyltransferase expression and/or function includes detection of a UDP-glucuronosyltransferase gene deletion polymorphism in the subject. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11760169-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11760170-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11636870-B2 |
priorityDate |
2009-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |