| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f6618ffa97d621cdfe9437fd02fcb7a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e918897df3fb82155bcf77fd4d115fa9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e3b0d965d236952081e2ddd9b265e8a0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9fa07f5b631bb39ecd22144f25e42ef |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0534 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-36082
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-4094 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N1-18 |
| filingDate |
2009-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2013-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dd35844a4945b3bc6b41581a8ad3b06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4719b4b57a6c8fd783df0a2f598077a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77e8bd19ffafc4ba3aad48440701e517 |
| publicationDate |
2013-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8473060-B2 |
| titleOfInvention |
Apparatus and method for modulating neurochemical levels in the brain |
| abstract |
A treatment for Parkinson's Disease uses a stimulus electrode implanted in a subthalamic nucleus with a chemosensor implanted in a globus pallidus pars interna (GPi) of the subject. A level of a neurochemical is sensed with the chemosensor, and compared to a desired level. When the level of the neurochemical is less than desired, an electrical stimulation is provided to the stimulus electrode. In alternative embodiments, the neurochemical sensed is glutamate or dopamine. An alternative system uses a chemosensor implanted in the striatum instead of the GPi. An alternative system for treating benign essential tremor uses a stimulus electrode implanted in the thalamus with feedback taken from a chemosensor in the striatum. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9841403-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11154718-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10029101-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9603522-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11040197-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012165634-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10441791-B2 |
| priorityDate |
2004-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |