| abstract |
In its many embodiments, the present invention provides a novel class of chroman compounds of formula I as α2C adrenergic receptor agonists, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of prepaxing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more conditions associated with the α2C adrenergic receptors using such compounds or pharmaceutical compositions. n n n n n n n n n n n n whereinn J is: n n n n n n n n n n n n n n n n n Z is —[C(R c )(R c )] x —,n wheren x is 1, 2, or 3. |