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filingDate 2012-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2013-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8455817-B2
titleOfInvention Sample component trapping, release, and separation with membrane assemblies interfaced to electrospray mass spectrometry
abstract A method and apparatus to trap, release and/or separate sample components in solution passing through a channel with or without packing material present by passing ion current through the channel driven by an electric field. A portion of the ion current includes cation and/or anion species generated from second solution flows separated from the sample solution flow path by semipermeable membranes. Cation and/or anion ion species generated in the second solution flow regions are transferred into the sample solution flow path through ion selective semipermeable membranes. Ion current moving along the sample solution flow path is controlled by varying the composition of the second solutions and/or changing the voltage between membrane sections for a given sample solution composition. The sample composition may also be varied separately or in parallel to enhance trapping, release and/or separation efficiency and range.
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Total number of triples: 56.