| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c8186c13bdad71fb2c9f1838787fa5b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e8bf117c4f6e891bbae12a258082bf6d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f0e68e45f09566a71c32f00e2e4536a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07f8378d083de25066eab97fe4aa1c5c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54393
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54373
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5432
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-45 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-75 |
| filingDate |
2010-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2013-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5f5daa8e5ebb9d7ace8a0959b254be2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82933e38625f0053a437d2a95000bd53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27f50ef76850ecab8632db4b8bdfd25d |
| publicationDate |
2013-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8450118-B2 |
| titleOfInvention |
Method for detecting binding interactions between membrane proteins and analytes in a homogenous assay |
| abstract |
Devices and methods for detecting interaction between components associated with lipid membranes and analytes are described herein. In certain methods, a surface of a compartment of a device is coated with a material that attaches to lipid membrane from a sample. An analyte is introduced and interaction is detected, for example, by back scattering interferometry. In another method, a surface is passivated with a material that does not bind a lipid membrane. A sample is introduced that contains a membrane comprising a component for testing and an analyte. Interaction is detected. In a third method, a channel is filled with a first liquid that does not comprise a lipid membrane. A bolus of a second liquid that comprises a membrane comprising a component for testing and an analyte is introduced under laminar flow conditions so that a leading edge of the second liquid does not completely displace the first liquid in a sensing area that is interrogated by optical methods, for example, a laser. Interaction between the analyte and the component is detected. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10627396-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11143649-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9273949-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9638632-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11293863-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10900961-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10261013-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9562853-B2 |
| priorityDate |
2009-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |