| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bd3f413aacd39c819d18e633c170041d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3a337419ae93b16c61a50419aee18f76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6945892aecdb4683147f2a5d09f6db41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9dd7997daab2fbc87a8aca25a1862ef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e4e38941903edd2a750925993651dffe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61872ea8adb4f156fecb64cac9c07dbf |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G69-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 |
| filingDate |
2007-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2013-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8752d96f259226ca61512a5ce89c7575
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20f380ad7cd6638ac6d0190cb9fd3445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1b64f6fef51881e402f4f30f2dd13d1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a0f0d7b23c6e56f9837ff48ea304c7b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_329767b81eec7e81ee82f1b104a20b5b |
| publicationDate |
2013-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8445627-B2 |
| titleOfInvention |
Alkylene-dicarboxylate-containing biodegradable poly(ester-amides) and methods of use |
| abstract |
The invention provides new aliphatic diester-di-acid-containing PEA polymer compositions with significant improvement in hydrolytic degradation rates as compared to aliphatic di-acid-containing PEA polymers. The di-acids used in the invention PEA compositions include non-toxic fatty aliphatic homologs. These molecules inherently contain two-ester groups, which easily can be cleaved by biotic (enzymatic) and abiotic hydrolysis. Additional di-acid-type compounds useful for active polycondensation are α,ω-alkylene dicarboxylates composed of short aliphatic non toxic diols and di-acids. In addition, the invention PEA polymer compositions optionally can include a second monomer, such as a C-protected L-lysine-based monomer, to introduce additional chain flexibility into the polymer. The invention PEA polymer compositions are useful for delivery of bioactive agents when administered internally. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10849944-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10772964-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11564894-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11413319-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11684587-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006286064-A1 |
| priorityDate |
2006-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |