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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00
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filingDate 2009-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb8c412f276b5371e4668ccf28789d3e
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publicationDate 2013-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8436157-B2
titleOfInvention Method for the production of sucralose
abstract The present invention provides a method for producing sucralose from a feed stream including a sucrose-6-acylate in a reaction vehicle. The method includes:n (i) reacting the sucrose-6-acylate with a chlorinating agent in order to chlorinate the 4, 1′ and 6′ positions of the sucrose-6-acylate; (ii) quenching the product stream of (i) with an aqueous solution of a base to provide a sucralose-6-acylate and the chloride salt of said base, wherein the concentration of the aqueous solution of the base is sufficiently high such that at least a portion of the chloride salt of the base is formed as a precipitate; (iii) either:n deacylating the sucralose-6-acylate by treating the product stream of (ii) with a base and thereafter removing precipitated salt to provide a product stream including sucralose; or: removing precipitated salt from the product stream of (ii) and thereafter deacylating the sucralose-6-acylate by treating with a base to provide a product stream including sucralose; and n (iv) isolating sucralose from the product stream of (iii).
priorityDate 2008-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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