http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8415098-B2

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filingDate 2010-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70cc18e36ccc8d4e18dc7e8ba6a666d6
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publicationDate 2013-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8415098-B2
titleOfInvention Method for isolating specific genomic regions
abstract Provided is a method for specifically isolating any genomic region while maintaining interaction of the genomic region with its interacting molecule(s). According to the method comprising the following steps 1 to 5: n Step 1: n n n n n preparing a cell in which a DNA fragment having a recognition sequence(s) for an exogenous DNA-binding molecule is inserted in genomic DNA of a genomic region to be isolated;n nStep 2:n n bringing genomic DNA of the cell into contact with an exogenous molecule at least having a DNA-binding domain of the exogenous DNA-binding molecule;n nStep 3:n n performing a treatment for maintaining interaction of the genomic DNA of the cell with a molecule(s) interacting with the genomic DNA;n nStep 4:n n performing a treatment for fragmenting the genomic DNA; andn nStep 5:n n allowing a complex to be formed by binding of a molecule capable of specifically binding to the exogenous molecule, and then collecting the complex,n nspecific genomic regions can be specifically isolated while kept interacting with their interacting molecules.
priorityDate 2009-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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