| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4239783a50609f52e7c767e426db33bd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78587acbfc8d4c9e9ac3baa7021087d7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f31aad9121371d74a12cbc13235cc5ee |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-661
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-685
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N57-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-33 |
| filingDate |
2008-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2013-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a5178f57522b51322d0dc3fb9ed2a51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c242251e2df5cda6efc0007d9ab99790 |
| publicationDate |
2013-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8410085-B2 |
| titleOfInvention |
Phospholipid compositions and uses thereof |
| abstract |
We have discovered that phospholipids diundecanoyl (C11:0-C11:0) and dilauroyl (C12:0-C12:0) phosphatidylcholine (PC) act as agonists of the LRH-1 receptor. We have also shown that administration of these lipids to diabetic mice reduces blood glucose levels. On the basis of these discoveries, the present invention features compositions that include these lipids and structurally related lipids. Also featured are methods of treating metabolic disorders and inflammatory bowel disease, lowering blood glucose levels, and increasing LRH-1 receptor activity in a subject by administration of these lipids. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9512406-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10227565-B2 |
| priorityDate |
2007-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |