Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_46846b85349e095674ab3a4131dd8ff2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b17177477b351b6973f8ad48d994165a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_499e5d793d254659e85282823c0d6421 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b3a1cbf71f9ce9eac8229bec7dc10ea7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb0af37a7c5e61a384434c901eeb9cb6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1763f7f78d01cad638210d060676591a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_562e4af016953c0a80e09960559ed0d2 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-16 |
filingDate |
2005-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2013-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_538a00ae44ea749254f886fa867cf1f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f23754eac0703e49603a51096d52216 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efcec4961ea197ac6ff0d5b754aa3194 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a9b94d7b81894c044adc13d0bbebfc5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e6b96c34047717019f4d8fa3328cc34 |
publicationDate |
2013-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8399241-B2 |
titleOfInvention |
Modulators of alpha-synuclein toxicity |
abstract |
Disclosed are compositions and methods for modulating expression of genes that function at the step of ER of Golgi trafficking. Compounds that modulate expression of these genes of activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to threat of prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10106803-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9738898-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10428335-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011053857-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11261453-B2 |
priorityDate |
2004-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |