| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac096c324192fc8b3e6d2e9830d6075f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b0e7c7e52a871c784444cc7390cb3baa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fb4c350d2d28295de7096d5980b59dea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8a143113a8426bd57def2ea84d70df56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c81598adf8f9f5e808a4ca3749cd5e38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6e9bbc4751f5dce89807f1b81221e2b1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-108
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-052
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0312
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0271
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8778 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-00 |
| filingDate |
2008-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2013-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c31120fb239df0471efb9193c21533c9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec64cb26b4b3b9ac2c5c82cd3d3a6d5d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12b08935ed3bc7539626fc8a30f7ab46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98bb0cb15b30f9ee1b959554c03d54ac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd47522b1f5cbc3444d792b0b6d46072 |
| publicationDate |
2013-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8389794-B2 |
| titleOfInvention |
Transgenic pig as a model of Alzheimer's disease |
| abstract |
The present invention relates to a modified pig as a model for studying Alzheimer's disease. The modified pig model displays one or more phenotypes associated with Alzheimer's disease. Disclosed is also a modified pig comprising a modified human and/or porcine APP gene, and/or PS1 gene, and/or a transcriptional and/or translational product or part thereof. The invention further relates to methods for producing the modified pig; and methods for evaluating the effect of a therapeutical treatment of Alzheimer's disease; methods for screening the efficacy of a pharmaceutical composition; and a method for treatment of a human being suffering from Alzheimer's disease are disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11234418-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10306873-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10278372-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10993419-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9888673-B2 |
| priorityDate |
2007-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |