| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a23768dbf9d8ef98eeeaa67e8b3127a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b62bc1c79be590de4dd195334b04d46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df0dfe6adcb603b8f2b16e29b863c6dd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6a2cc904b7a14e425d8108729f1d0fa5 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-438 |
| filingDate |
2010-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2013-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3a9b455ad0c65631c0a9cc1798cfb4a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46ee60f6e820a3acb431085b1814e6f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a52d048ffb06da7e8443c08b0bc957fb |
| publicationDate |
2013-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8383643-B2 |
| titleOfInvention |
Spiro compounds useful as inhibitors of stearoyl-coenzyme A delta-9 desaturase |
| abstract |
Heteroaromatic compounds of structural formula (I) are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; diabetes; neurological disease; metabolic syndrome; insulin resistance; and liver steatosis. |
| priorityDate |
2009-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |