| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69108fc12b940ede105638f37f06080b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2713f88581749fe89a3f379aeb94ce4c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0f9dcee761128a416b75a70109293e04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da082a8f0c36fe9afbdb7e705f4b35d3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-2991 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-533
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0017
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0065
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-587 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01F17-00 |
| filingDate |
2009-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2013-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdcefd1eb944c2bd9d3389b4fa692963
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc6d62381c137c774528571370360891
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_acb5b3833777708f00fde7b66c9955bf |
| publicationDate |
2013-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8372435-B2 |
| titleOfInvention |
Modular monolayer coatings for selective attachment of nanoparticles to biomolecules |
| abstract |
Nanoparticles are functionalized for use as bio-imaging probes using a novel, modular approach. Particle surface modification is based on a phosphonate monolayer platform on which was built a multi-segmented, multi-functional film: the first segment provided hydrolytic stability, the second aqueous suspendability, and the third, selectivity for cell attachment. In vitro imaging experiments visualized nanoparticle-cell surface binding. Peptide-derivatized nano-particles were not displaced from cells by soluble peptide. Methods for coating the host particles and use of rare earth ion-doped particles in imaging methods and photodynamic therapy methods are also disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015045664-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10080811-B2 |
| priorityDate |
2008-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |