Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bfd2c2f2bb0026db4d870cdf700616df http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9de52ca05e136e73a771948936f7db1b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4a50180a63b7abac2bd21da644a87c21 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T29-49885 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2250-0068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2250-0067 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L33-00 |
filingDate |
2010-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2013-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b6205ec194d81662f33b5dd48a4ed42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b4109b9961d1a783074f340a6441852 |
publicationDate |
2013-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8367151-B2 |
titleOfInvention |
Stent coating for eluting medication |
abstract |
A vascular stent comprising a drug-eluting outer layer of a porous sputtered columnar metal having each column capped with a biocompatible carbon-containing material is described. This is done by placing the stent over a close-fitting mandrel and rotating the assembly in a sputter flux. The result is a coating that is evenly distributed over the outward-facing side of the stent's wire mesh while preventing the sputtered columnar coating from reaching the inward facing side where a smooth hemocompatible surface is required. The stent is then removed from the mandrel, exposing all surfaces, and finally coated with a layer of carbon such as amorphous carbon or diamond-like carbon. The carbonaceous coating enhances biocompatibility without preventing elutriation of a therapeutic drug provided in the porosity formed between the columnar structures. The result is a stent that is adapted to both the hemodynamic and the immune response requirements of its vascular environment. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013004650-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011232278-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9773627-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011234362-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011232562-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8663317-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8764286-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8789366-B2 |
priorityDate |
2005-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |