Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2e1bc01093afa5baa8251b609a4c2c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b233e0f0d6d8829faa9380a29e2b1f93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b352be0236d6cf7a4a5ef3c67d305395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8bc3caf4f9838cbda2c59587e8504bb5 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-00 |
filingDate |
2011-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2013-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94a6ea82194dfe4085f87cfbddc3cb02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d158adf2fa6dc2d114d4db0339949065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1107bb9a7f08847338cde4b04fb9c66 |
publicationDate |
2013-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8350061-B2 |
titleOfInvention |
Synthetic analogs of bacterial quorum sensors |
abstract |
Bacterial quorum-sensing molecule analogs having the following structures: n nand methods of reducing bacterial pathogenicity, comprising providing a biological system comprising pathogenic bacteria which produce natural quorum-sensing molecule; providing a synthetic bacterial quorum-sensing molecule having the above structures and introducing the synthetic quorum-sensing molecule into the biological system comprising pathogenic bacteria. Further is provided a method of targeted delivery of an antibiotic, comprising providing a synthetic quorum-sensing molecule; chemically linking the synthetic quorum-sensing molecule to an antibiotic to produce a quorum-sensing molecule-antibiotic conjugate; and introducing the conjugate into a biological system comprising pathogenic bacteria susceptible to the antibiotic. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10807943-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10526278-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11247976-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017190116-A1 |
priorityDate |
2009-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |