Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_87b3ec41b4cb7ab4e4498c633cf972a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d0446a5bd77c7da68216fc2e3f05d48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10c61cc69ea28b896d0ea3ecf1bc395e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d3a414708d0b3662e3db3fc5d0031b97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28715035ced4f6bb2b88e56072e7ff2c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5079 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-00 |
filingDate |
2008-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2013-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b553835bd357847d21a38b3882991f82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b1c151a23e69114c12645288a47ae47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ddc58c9ddccda150e51fd565ff33ec4 |
publicationDate |
2013-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8349553-B2 |
titleOfInvention |
Jasmonate based assays for identifying compounds that selectively inhibit mitochondrial bound hexokinases |
abstract |
The present invention provides compositions comprising compounds that selectively bind to hexokinases thereby promoting dissociation of these enzymes from mitochondria, and methods of use of such compounds and compositions to induce cell death in diseases and disorders characterized by the high levels of mitochondrial bound hexokinase. The present invention further discloses methods and assays for detecting and identifying molecules having these activities. |
priorityDate |
2007-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |