| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2d77926fc1a09c9f03aba057dfac5825
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_035cb85c30007d4d98bc31b31dee91b5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bba710e7aaa56d8ab15a910fcd3dc5f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-755
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-755
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-37 |
| filingDate |
2008-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea42d8e0d5bb1f2a3c5b52d3fc0c87d2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9df4eae864011624ec928a2c1a9e3145 |
| publicationDate |
2012-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8338571-B2 |
| titleOfInvention |
Recombinant factor VIII having increased stability |
| abstract |
The present invention relates to a recombinant factor VIII that includes one or more mutations that result in enhanced stability of both factor VIII and factor VIIIa. Methods of making and using the recombinant factor VIII, and pharmaceutical compositions containing the same are also disclosed. The present invention further relates to an isolated nucleic acid molecule that encodes the recombinant factor VIII, as well as DNA expression systems and host cells containing the isolated nucleic acid molecule. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015037301-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9914764-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10266583-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9982035-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10351619-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014152530-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3427744-A1 |
| priorityDate |
2007-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |