Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_885cfdb9f042241b5f731e23f41b7f3f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d3db7923b8399b8e052eecd89c2dd551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_40da09681f3bd00bc88a58d1dfd51897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_16bbdf8d6d0741262911d51e5c9fee7f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb7ce8745175865c6357f7d5fe7fccf5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8fe512dcfa7132c5840eded49a36033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b2aee161273e324044af49f5ad095cbe |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57415 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate |
2011-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5edba6aed3e840b33eb20f09804b07e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cc383aabfa564a20bca001ad7cb38c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eeb75da345bbdfb2a375ae52087013f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_192861b2c44e943cdfba6c8845c900b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d3523e9d548a0b7e6ee40a5f9fcab3f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19f522fd5b420dbcf54432b98fcb808e |
publicationDate |
2012-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8338456-B2 |
titleOfInvention |
Cut-point in PTEN protein expression that accurately identifies tumors and is predictive of drug response to a pan-ErbB inhibitor |
abstract |
A cut-point in the quantitative measurement of PTEN protein expression that accurately identifies tumors with two inactivated alleles of the PTEN gene. Patients with a normalized PTEN score of PTEN null will be treated with a pan-ErbB tyrosine kinase inhibitor. A normalized PTEN protein expression score is obtained by comparing the tumor PTEN OD expression value with the non-malignant PTEN OD expression value. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10729672-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9139558-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10111868-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9630946-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10596162-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9265784-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10603314-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9511063-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10035788-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9211264-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9211291-B2 |
priorityDate |
2010-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |