Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b0bbe8e24657b1d6fc23b70d99565ecd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9ff1b98c6f49c08929170df4355e9885 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d0cbf44651efe1d50990f98f9b282cde http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a555bd18827bb277757c67b9086d8ba |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-40 |
filingDate |
2007-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9acc5c2e6d260fcb658aa2478bbd229 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e365eafaef905a32a60feddddd4b2ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8f547f87da462dcd5434455eda7ad74 |
publicationDate |
2012-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8334389-B2 |
titleOfInvention |
Process for the preparation of pleuromutilins |
abstract |
A process for the preparation of 14-O-[(N-(3-methyl-2-amino-butyryl-piperidinyl)sulfanyl) acetyl]mutilins of formula (I) feasible for large-scale production of high purity products, and wherein the carbon atom at the piperidine ring attached to the sulphur atom is either in the (S)-configuration or in the (R)-configuration, and a new crystalline form of 14-O-[(N-3-methyl-2-(R)-amino-butyryl-piperidine-3(S)-yl)sulfanyl)acetyl]mutilin-hydrochloride. |
priorityDate |
2006-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |