| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d70be33d72ac51a22df3d94f31d10d3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e3bb613a31a6b1402d0907925253dc1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4795a7fc3e53f1b8341ad5e4b7489d64 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02E50-10 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y114-15003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0077 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 |
| filingDate |
2009-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8b6361374cff9432fafa22eb98c6f2d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1153283f3a0bfb944a027a1e37aa0186 |
| publicationDate |
2012-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8309333-B1 |
| titleOfInvention |
Regioselective alkane hydroxylation with a mutant AlkB enzyme |
| abstract |
AlkB from Pseudomonas putida was engineered using in-vivo directed evolution to hydroxylate small chain alkanes. Mutant AlkB-BMO1 hydroxylates propane and butane at the terminal carbon at a rate greater than the wild-type to form 1-propanol and 1-butanol, respectively. Mutant AlkB-BMO2 similarly hydroxylates propane and butane at the terminal carbon at a rate greater than the wild-type to form 1-propanol and 1-butanol, respectively. These biocatalysts are highly active for small chain alkane substrates and their regioselectivity is retained in whole-cell biotransformations. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018007289-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11034938-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3336180-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20190025955-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109689863-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109689863-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10202620-B2 |
| priorityDate |
2009-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |