| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_763965ef9719ac81ee203f4a2c9e0cd0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_500cd7e7b1718ada814bc125e069348b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e822017c18accbcbadc502f8cf19384
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a887bcece03057c9fd2a8dd8bdd72f1d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68091fe0a620e13f2f99b0fe0b4e87cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d5af24bfbb650ae2e7ddf95747271e81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d0edf42b4758334de66fe685237ececb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-98 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6851
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6842 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34 |
| filingDate |
2006-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86c9d5bb8cd2c21b832ca2bc9d3c4970
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f21ff17948004d3d261437bf7081d2e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fec016c5db6442addb83964042208df
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eda5f794c03b6b70485a7170e4c5e3ea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35fbf37f6c575b831765bcad9cb985e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97f2673e205407630091fa6050ae1c06 |
| publicationDate |
2012-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8304206-B2 |
| titleOfInvention |
Mass spectrometry assays for identifying compounds that activate deacetylases |
| abstract |
Provided are methods for determining the activity of proteins that modulate the acetylation state of a protein substrate. The methods may be used for determining both acetyltransferase activity and deacetylase activity. The methods utilize mass spectrometry for determining the acetylation state of a substrate peptide. The methods may also be used to identify compounds that modulate the activity of a protein having acetyltransferase or deacetylase activity. In some embodiments, a compound that modulates a deacetylase is an activator of the deacetylase. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008293081-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015109082-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11726088-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10788492-B2 |
| priorityDate |
2005-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |