| abstract |
A compound having the structure n nwherein R is an angiotensin receptor antagonist active group, and Y isn nY is selected from the group consisting ofn n nR 1 is selected from the group consisting ofn —O—C 1-6 alkyl, —O-aryl, —O-heteroaryl, —O—C 3-8 cycloalkyl, —C 1-6 alkyl, -aryl, -heteroaryl, and —C 3-8 cycloalkyl;n nR 2 and R 3 are independently selected from the group consisting of hydrogen and C 1-4 alkyl, or a pharmaceutically acceptable salt or hydrate thereof, which is useful for treating hypertension. |