| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_57df48b0c0f3e613a44fd627f2a02028
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4acdd0549d018610d989d547a44d1dc4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e056cd3d07728da02bb12211ce3831c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4725
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-04 |
| filingDate |
2005-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e1c9df99a2c478ed37733ec5b118874
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eef5a6f01fa84c88d982a69592d5691e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72fc484b21e9dddb7080f413ddc350c2 |
| publicationDate |
2012-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8293764-B2 |
| titleOfInvention |
Compositions and methods for disruption of BRCA2-Rad51 interaction |
| abstract |
Contemplated compounds disrupt interaction between BRCA2 and RAD51, likely by binding to RAD51. Based on the crucial role of the BRCA2-RAD51 complex formation in DNA repair and the role of RAD51 in the control of entry into S-phase from G1, numerous compositions and methods are presented. Among other advantageous uses, contemplated compounds may be employed as protective agents for non-neoplastic cells in chemotherapy before exposure of the cells to a chemotherapeutic drug, and/or as DNA-damage sensitizer for neoplastic cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10421753-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10730864-B2 |
| priorityDate |
2004-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |