| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec3d7a9a543c4214ef75cdabb2d0e04b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e6832eb719b89d4878d23769dae17e3b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e4aa609ba3f79ef0e55bfbb2ca8bdc9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4335de535fbca28c420b0f00d0b988f4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e9d856556cbc482112b5716c19703c3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b4c59ed9a4f7a8e97843fdacda20ab7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5254
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-525
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16161
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16134
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2469-20 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1018
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56983
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-145 |
| filingDate |
2010-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0962b82346912463594eb33e4052b36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab9a622e55ae69ffc620e56a44a7474d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed935dd8b619c50400837315c8af033f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77c8b71bac27ed690bb2802cbe2721e0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8a6587c3d2ccadf108a89d7dcee2b87 |
| publicationDate |
2012-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8293247-B2 |
| titleOfInvention |
Modified influenza virus for monitoring and improving vaccine efficiency |
| abstract |
The immunogenicity of the influenza virus hemagglutinin (HA) molecule may be increased by substitutions of amino acids in the HA sequence. The substitution of specific HA residues, such as asparagine at position 223 of H5 HA, increase the sensitivity of the hemagglutinin inhibition (HI) assay by altering receptor specificity and/or antibody-antigen binding. HA molecules containing such substitutions will be useful in the development of diagnostic reference viruses and improved influenza vaccines. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011033494-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9499850-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8709448-B2 |
| priorityDate |
2005-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |