Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7fa45d9a0359a180d722e28a46b6b982 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f4ab78c35d5dbac561c0cba50a0af57d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b8521b99ef9f9b0a7d38b4bb931d519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f67dce009e22085b599fd6103e355507 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eaa3cf710f615dab717de98abcc6d27f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10bd7baf82e51a4b37e0e24ee06d11ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fe7e5f6d4fc870b7202b3b645768b531 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
filingDate |
2008-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5aafdc36f27cff4524ecea89833698f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_570263ae03a41735ba0c284766360565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1d5b328eb5ae37a2b2a3d35f8166a30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_807f80585739ebbeb046a84e22dddbe0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22c7ce9322c0d1995548e34bffd1fbf5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed5eb56687dd34ffbb434c3556eb9c32 |
publicationDate |
2012-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8288108-B2 |
titleOfInvention |
Expression profiles for predicting septic conditions |
abstract |
A rapid, safe method for predicting sepsis, or a condition similar to sepsis, in a mammal is disclosed, which comprises the following steps:n I) isolating RNA from a biological sample of a mammal; ii) labeling the isolated RNA of step I) with a detectable marker; iii) hybridizing the labeled isolated RNA of step ii) with at least one DNA of genes Seq.-ID 1 to Seq.-ID 6705 (Table 1), which is spotted onto a microarray and which is a sepsis-specific gene or gene fragment, under the reaction conditions for hybridizations; iv) quantitatively recording labeling signals of the hybridized RNA of step iii) in an expression profile; v) comparing the expression profile of step iv) with a control sample with respect to a stronger or weaker expression of genes or gene fragments which are specific for sepsis; and vi) combining the expression profile of step v) with protein- and metabolite patterns of the biological sample. |
priorityDate |
2005-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |