Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b8468c5085a58c8a4fc3ee4178722562 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_74b7b50944d8e1960440fb1f5440b7fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e68c9532182cff127ba3977cc9753b1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2851 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-464 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 |
filingDate |
2011-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e8ad22e32dd471511e1e6ec8f1d58d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a244ca39558092a11a73040dee21a57 |
publicationDate |
2012-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8282924-B2 |
titleOfInvention |
Hybrid antibodies |
abstract |
Hybrid antibodies and/or hybrid antibody fragments and methods of making them are provided. In one embodiment the hybrid antibodies and/or hybrid antibody fragments 5 contain heavy and/or light variable regions that contain two or more framework regions derived from at least two antibodies. In another embodiment, at least two of the framework regions are classified in the same germline gene family. In one embodiment, at least two framework regions are classified in the same germline gene family member. The hybrid antibodies or hybrid antibody fragments may contain human framework regions and 10 nonhuman CDRs. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011313134-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9067991-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010047241-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11472871-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9156905-B2 |
priorityDate |
2001-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |