Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7828e97b7f7aca611ba772ddd6fb51e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a83c17cb0f12a84f87fae910d23d7d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e70c0aeade92d7571d955d3b90ea06e |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-6427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0071 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-64 |
filingDate |
2009-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_552d1c1567ee8a3a4c332a5ce3d04b16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f64001f50657bf8b3a6248cb43908bc1 |
publicationDate |
2012-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8268598-B2 |
titleOfInvention |
Mutant Δ5 desaturases mutated in the heme-binding motif (HPGG) and their use in making polyunsaturated fatty acids |
abstract |
The present invention relates to mutant Δ5 desaturases, which have the ability to convert dihomo-γ-linolenic acid [DGLA; 20:3 ω-6] to arachidonic acid [ARA; 20:4 ω-6] and/or eicosatetraenoic acid [ETA; 20:4 ω-3] to eicosapentaenoic acid [EPA; 20:5 ω-3] and which possess at least one mutation within the HPGG motif of the cytochrome b 5 -like domain. Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding Δ5 desaturases, along with a method of making long chain polyunsaturated fatty acids [“PUFAs”] using these mutant Δ5 desaturases in oleaginous yeast, are disclosed. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8614075-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014093910-A1 |
priorityDate |
2008-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |