Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7cefe86253c64eeb654f22633bc1404a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc0b62f11f002cd4b5b01f88dcb491fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b9b30d0f025d287c94365b3599c47d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_00a421ab71bd49a451d0a49d23a082c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_387b2a586e2fc8cbe94192ba4313a85e |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4196 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 |
filingDate |
2009-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22a8ba8aa726b5a5ea67c6129299daf2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db654a3cf58a844aa84caa4bb1a785ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_183a56b8a0cafd3d6ccdee072cc2562b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_303e6e6dc446676e1133e7a80ee10352 |
publicationDate |
2012-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8258137-B2 |
titleOfInvention |
Process for release of biologically active species from mesoporous oxide systems |
abstract |
A process for the release of a biologically active species comprising the steps of:n providing a mesoporous oxide-based material having structural order and at least one level of porosity; fixing or immobilizing said biologically active species in said ordered mesoporous oxide; and providing said ordered mesoporous oxide with said fixed or immobilized biologically active species in vivo thereby realizing intraluminally induced substantially pH-independent supersaturation of said biologically active species resulting in enhanced transepithelial transport; wherein said biologically active species is a poorly soluble therapeutic drug classified as belonging to Class II or Class IV of the Biopharmaceutical Classification System and said ordered mesoporous oxide has a pore size in the range of 4 to 14 nm. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10729646-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10835495-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014078435-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022354796-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018008615-A1 |
priorityDate |
2008-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |