| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_25bcf7253a2bb95e98247f0d06202b12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c3ef2a506a09ab6bd3b08cce501414d3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c29f0066039affc2d268107647787069
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2245aefaea2a24047376999b2602c8b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-4202
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-31678
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-30767
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-3804
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2310-00976
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2310-00023
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-4241
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61C8-0012 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61C8-0013 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61C8-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-42 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-00 |
| filingDate |
2010-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67e92beb69683c67b6fc1780d275fed3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b122ee19d3d02132a05d26f8a2fe4e4f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b876676cf5a78a07d626811ecbd63fd |
| publicationDate |
2012-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8257728-B2 |
| titleOfInvention |
Metal implant coated under reduced oxygen concentration with osteoinductive protein |
| abstract |
The present invention relates to a method for producing a device comprising the steps of (a) providing a solution comprising dissolved osteoinductive protein, (b) contacting the solution of the preceding step with a carrier containing a surface of metal or a metal alloy, (c) allowing coating of the surface of said carrier with said dissolved protein and (d) drying of the coated carrier obtained in step (c) wherein steps (b) to (d) are carried out under a reduced concentration of oxygen. The invention also encompasses a device obtainable by the method of the present invention. Moreover, the present invention relates to a pharmaceutical composition comprising the said device and to the use of the device for the preparation of a pharmaceutical composition to be used for an accelerated osseointegration and new bone formation. Finally, the present invention relates to a kit comprising the device of the present invention. |
| priorityDate |
2002-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |