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filingDate 2006-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2012-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67864aed6697749db6fbc66bbaab99d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ce23211fad5525f64d584bc559aa4e3
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publicationDate 2012-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8257680-B1
titleOfInvention Catalytic radiofluorination
abstract One aspect of the present invention relates to a method of preparing radiofluorinated substituted alkyl, cycloalkyl, aryl, and alkenyl compounds. In a preferred embodiment, potassium fluoride-18 is used. Another aspect of the invention relates to arylammonium compounds containing fluorine-18 that are useful as imaging agents. In certain embodiments, the ammonium compound is a tetraaryl ammonium salt. Another aspect of the invention relates to arylsulfonium compounds containing fluorine-18 that are useful as imaging agents. In certain embodiments, the sulfonium compound is a triaryl sulfonium salt. Another aspect of the present invention relates to a method of obtaining a positron emission image of a mammal, comprising the steps of administering to a mammal a compound of the invention, and acquiring a positron emission spectrum of the mammal.
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priorityDate 2004-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 881.