Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9a95353a8abb95dc3120e898b03090ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_efd0171dfabad66df8bda9f73fdcd767 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5dd388a5130b0bdede0fdfc6c2af6ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb25dcc4574b4cc252c9b07b6ec3e9d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b013df7cb43953f221c347c59f19b946 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_96220a928d1baa08ae13c3d0c0ec1bc3 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56966 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-567 |
filingDate |
2011-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c86184469b7b430fa07d10706bfcbcdf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96b1f873eeb82f9888b0dda0d9d8bcd9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52085314692cf30a5b3a299069427711 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1538ca5afd4e9a7dddd51f8cdbee4182 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e299dcb8ba729ef14dff26eb5867afeb |
publicationDate |
2012-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8247186-B2 |
titleOfInvention |
Monoclonal antibodies and their use |
abstract |
Isolated monoclonal antibodies are disclosed herein that specifically bind a cell surface antigen expressed on the human pancreatic endocrine cells or a subset thereof, and/or a precursor thereof. Isolated monoclonal antibodies are also disclosed herein that specifically bind a cell surface antigen expressed on human pancreatic exocrine cells or human ductal cells. Humanized forms of these antibodies, and functional fragments of these antibodies, are also disclosed. The antibodies can be conjugated to an effector molecule, or a detectable marker. These antibodies are of use to detect and/or isolate pancreatic cells or a subset thereof. Methods of treating a pancreatic tumor are also disclosed. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10208108-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016152732-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10233256-B2 |
priorityDate |
2006-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |