http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8242082-B2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd569fbfa1953ca9b7b375510e4d2763 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c604cc6e63b34459620c3dfd40c473be http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5710a48147603e46ef85e7799620e7dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_583e6bdb186d78a2ac3fae18af79ea1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fed86066f02930e2ed62956e99e7f205 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4723 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate | 2008-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2012-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfa69647be21908cf2a7d427d8bf8517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_566be6d3026013309008e2891b4384aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9b255a435cb53d5d705520e4e38500e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_332afb942eac1184fc6a3a270335ac3a |
publicationDate | 2012-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-8242082-B2 |
titleOfInvention | Antibacterial peptide |
abstract | The present invention provides a novel peptide based on CAP11 as well as provides an antibacterial agent, an LPS-cell-binding inhibitor, and a drug such as a bacterial-infection-treating agent or an endotoxin-shock suppressant, each containing the peptide as an active ingredient. The peptide has the following amino acid sequence (SEQ ID NO: 1): X01 X02 X03 X03 X04 X02 X03 X03 X05 X04 X03 X04 X02 X01 X03 X02 X05 X03 (wherein X01 represents a cationic amino acid residue or a polar uncharged amino acid residue, X02 represents a non-polar amino acid residue, X03 represents a cationic amino acid residue, X04 represents a non-polar amino acid residue or a cationic amino acid residue, and X05 represents a non-polar amino acid residue or a polar uncharged amino acid residue). Each of the antibacterial agent, lipopolysaccharide-cell-binding inhibitor, and drug (e.g., bacterial-infection-treating agent or endotoxin-shock suppressant) contains the peptide as an active ingredient. The present invention also provides for a peptide comprised of a sequence of cationic and non-polar or polar uncharged amino acids forming an α-helix wherein the amino acids are arranged along the α-helix such that when represented as a helical wheel, there is a substantial bi-lateral symmetry between cationic versus non-polar or polar uncharged amino acids. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11174288-B2 |
priorityDate | 2004-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 318.