Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c3cae946f05865a11b2e7af55677440 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f5e9370749f3a1775e3f47a2fc3825b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fed053e0e3b6c5a4a29eadb3c3fd40c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_419b274e49a2979ec9e8312bec48e004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_15d4d87561fb292a191cd038a19f3a7b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55594 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55555 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B5-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-06 |
filingDate |
2011-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4df80e450a69b40c49aa154597b58415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_feaed7b6a10521521604c898ccad9aef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a3532cd82aa22fbc57e2fd7ba8845ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31e3a1b82d81ee279674310137916d95 |
publicationDate |
2012-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8241610-B2 |
titleOfInvention |
Adjuvant combinations of liposomes and mycobacterial lipids for immunization compositions and vaccines |
abstract |
The present invention provides a vaccine adjuvant consisting of a combination of a surfactant i.e. dimethyldeoctadecylammonium-bromide/chloride (DDA) and a lipid extract from Mycobacterium bovis BCG. The total lipid extract contains both apolar lipids, polar lipids, and lipids of intermediate polarity of which the apolar lipids were found to induce the most powerful immune responses. The total lipids may be extracted with chloroform/methanol and re-dissolved in water before the addition of surfactant. This preparation may be used to induce prominent cell-mediated immune responses in a mammal in order to combat pathogens, or as a treatment for cancer. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022081764-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013151736-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015034925-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015034928-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013151666-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022152939-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023161350-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4011451-A1 |
priorityDate |
2003-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |