http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8218878-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a2f1d0f97b5a1fa82dfdf69741f99b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dcb2819f484f702b4c74d0043ba9b727 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6439 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6408 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-44726 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-44778 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06K9-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-447 |
| filingDate | 2009-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7749e94aead707435ecedc3132149d20 |
| publicationDate | 2012-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8218878-B2 |
| titleOfInvention | Cumulative time-resolved emission two-dimensional gel electrophoresis |
| abstract | A new instrumental design is provided for in-gel detection and quantification of proteins. This new platform, called Cumulative Time-resolved Emission 2-Dimensional Gel Electrophoresis, utilizes differences in fluorescent lifetime imaging to differentiate between fluorescence from specific protein labels and non-specific background fluorescence, resulting in a drastic improvement in both sensitivity and dynamic range compared to existing technology. The platform is primarily for image acquisition of two-dimensional gel electrophoresis, but is also applicable to protein detection in one-dimensional gel systems as well as proteins electroblotted to e.g. PVDF membranes. Given the increase in sensitivity of detection and dynamic range of up to 5-6 orders of magnitude compared to existing approaches, the described invention represents a technological leap in the detection of low abundance cellular proteins, which is desperately needed in the field of biomarker discovery. |
| priorityDate | 2008-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.