http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8212090-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed6aa8b3904f29f1a564cd96f0052167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc2b03342511abc88f60c63f2acd96d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_17f17ee3a7656231e27d85c4c92bc270 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C17-206 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C22-00 |
filingDate | 2009-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2012-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f484bc8ddee612c4bf005678f4d0d81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecce7d490688f5cdf58d238bfabb76e5 |
publicationDate | 2012-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-8212090-B2 |
titleOfInvention | Methods for silver-promoted fluorination of organic molecules |
abstract | The methods of the disclosure may be used for the fluorination of organic compounds, and in particular aryl organic compounds other than just benzyl halogens. It is within the scope of the present disclosure, for organic compounds comprising an electrophilic carbon atom and a halogen leaving group to be fluorinated by the methods of the disclosure. One aspect of the disclosure provides methods of introducing a fluorine atom onto an electrophilic carbon atom, comprising mixing an insoluble basic silver salt, an organic molecule containing a leaving group, an aqueous solution of hydrofluoric acid, and a polar solvent:water composition; incubating said mixture at a temperature of about 20° C. to about 35° C., thereby obtaining a fluorinated organic product. |
priorityDate | 2008-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 200.