| abstract |
A device for implantation in a body vessel is provided. The device includes a frame that accommodates dynamic variation in the size of the vessel. At least one leaflet is attached to the frame. The leaflet is deformable between a first position allowing fluid flow in a first, antegrade direction and a second position restricting fluid flow in a second, retrograde direction. Methods for delivering the device to a body vessel and methods and kits for treating a subject using such a device are also provided. |