| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_edc9d381093026c7a5ba4abb0ca87686
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34155dba1162f12a41bdc24fab9e05ec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f78f54ca14939aa46c042b5f8098b330
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b02b2fafb5bb9e7027b873538a83c013
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4c8055526000e12af4150601a4f4d7c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 |
| filingDate |
2009-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4f122a1d315acd93235c13d99cce655
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bf73b85fca452a6c774868b00a5b294
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57211b2ac17e393a5eabd173c0359941
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e54bd821acd741d34eab237f60d4663 |
| publicationDate |
2012-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8206925-B2 |
| titleOfInvention |
Splice variants of human IL-23 receptor (IL-23R) mRNA and use of a delta 9 isoform in predicting inflammatory bowel diseases |
| abstract |
There is disclosed the cloning and identification of human IL-23R splice variants caused by alternative splicing of the IL-23R mRNA in human. Alternative mRNA forms occur through skipping one, multiple full exons or partial exons, within the IL-23R gene. A total of twenty-five (25) different IL-23R transcripts were identified. A novel exon deletion (exon 9) isoform in the interleukin 23 receptor is disclosed, denoted as Δ9. The present application also describes a quantitative assay to measure different IL-23R isoform. Detection of Δ9 isoform of IL-23R is predominantly present in colon and cervical tissues. A decrease in Δ9 is observed in inflamed colon tissues in Crohn's patients. There is disclosed a method of predicting Crohn's disease by measuring Δ9 isoform of IL-23R. |
| priorityDate |
2008-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |