Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_655de7d5ab04a139234ea8e143496a64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7475dcaf578d0c764b6442bfffc649fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bba710e7aaa56d8ab15a910fcd3dc5f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f819966ff2793d2ffd93b2937627f2d8 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
filingDate |
2009-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_786dfb67b3fcb583226ff59ae2e5cecc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d475c7bccad4f998fc29563384a129f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb768739f9ec89779e8843b1fa7634d7 |
publicationDate |
2012-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8188252-B2 |
titleOfInvention |
Rad51 derived cancer cell specific promoters for targeted anti-cancer therapy |
abstract |
Provided are compositions and methods for inhibiting growth of cancer cells. The method of the invention relates to delivering to cells an effective amount of a composition that contains a polynucleotide having a Rad51 promoter or a polynucleotide having at least 95% similarity to a Rad51 promoter. The Rad51 promoter is operably linked to a coding region for a cytotoxic agent. In vitro and in vivo results demonstrating effectiveness of the polynucleotides of the invention are presented. |
priorityDate |
2008-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |