http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8188152-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d0611d7df62403605072e9c1cd32f799 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eecd0d1c75e4c35ee7741c8e303cbd0a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b39f28aa914551cbba48b87784a7b83d |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N27-00 |
filingDate | 2006-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2012-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a9e632db21aa12fa594437ca72e1be9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d96ec82a05e462261ce8ff6ae983b74 |
publicationDate | 2012-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-8188152-B2 |
titleOfInvention | 2-aminoalcohols for the treatment of neurodegenerative diseases |
abstract | Use of a compound for the manufacture of a medicament for use in therapy of a neurodegenerative condition, wherein the compound is of formula (I): wherein R 1 is CHR 4 —OR 5 or CHR 4 —SR 5 , or aryl or heteroaryi optionally substituted with one or more groups R 6 ; R 2 is alkyl or is part of a ring with R 3 ; R 3 is H, alkyl or CH 2 (when forming part of a ring with R 2 ); R 4 is H or alkyl or is part of a ring with R 5 ; R 5 is aryl or heteroaryi optionally substituted with R 7 ; each R 6 is independently alkyl, CF 3 , OH, Oalkyl, OCOalkyl, CONH 2 , CN, halogen, NH 2 , NO 2 , NHCHO, NHCONH 2 , NHSO 2 alkyl, CONH 2 , SOMe, SO 2 NH 2 , Salkyl, CH 2 SO 2 alkyl or OCONalkyl 2 ; R 7 is R 8 or (CH 2 ) n OR 8 , R 9 , CF 3 , OH, OR 9 , OCOR 9 , COR 9 , COOR 9 , CONH 2 , CH 2 CONH 2 , CN, halogen, NH 2 , NO 2 , NHCHO, NHCONH 2 , NHCONHR 7 , NHCON(R 9 ) 2 , NHCOR 9 , NHCOaryl, NHSO 2 Me, CONH 2 , SMe, SOMe or SO 2 NH 2 ; R 8 is (CH 2 ) n OR 9 , (CH) n OR 9 , (CH 2 ) n COOR 9 or (CH 2 ) n COaryl; R 9 is alkyl or cycloalkyl; and n is 1 to 4; or a salt thereof. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010076068-A1 |
priorityDate | 2005-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 111.