http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8188112-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37b416a8c0d2b0f1c3d6026d932027af http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8a5ca71cfb45e6ea1084dc10ea405f10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0064fcbd7c45015c5bb7bb9f6985139a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1bcb0d04892c6e929ae9037f03e3ea4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_738da61ef2608ff0a6906f03daeada57 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2005-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2123f64b77c8f20d2ec210e6e480ccef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2eaa29778d81099d19697bd5cd4e16c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f57f4e8cb80f61fadb077ab1e282c3a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0605f13c33cf1a85a0d0f475933ef89e |
| publicationDate | 2012-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8188112-B2 |
| titleOfInvention | Naphthalamide derivatives having antiproliferative activity |
| abstract | The invention relates to compounds for use in medicine. The compounds are of general formula (I) as disclosed herein and the pharmaceutically acceptable salts, individual isomers and mixtures of isomers thereof, wherein X, X′ and X″ are independently O or S; Z is N or P; R3 is optional and is selected from the group consisting of optionally substituted C1-8 alkyl, optionally substituted C2-6alkenyl, optionally substituted C2-6 alkynyl, optionally substituted C1-6 alkoxy, optionally substituted C1-6 thioalkyl, optionally substituted C5-10 aryl, optionally substituted C6-11 alkylaryl, optionally substituted C1-6 alkylamino, optionally substituted C1-6 alkylcarbonyl, optionally substituted C1-6 alkylsulfonamino, optionally substituted (C1-C6)alkylsulfinyl, optionally substituted C1-6 alkylcarbonylamino, optionally substituted hetero(C4-C10)aryl, hydroxyl, halogen, cyano, nitro, amino, formyl, and thiol; R1, R2, R4, R5, R6, R7, R8, R9, and R10 are independently selected from the group consisting of hydrogen, optionally substituted C1-8 alkyl, optionally substituted C2-6 alkenyl, optionally substituted C2-6 alkynyl, optionally substituted C1-6 alkoxy, optionally substituted C1-6 thioalkyl, optionally substituted C5-10 aryl, optionally substituted C6-11 alkylaryl, optionally substituted C1-6 alkylamino, optionally substituted C1-6 alkylcarbonyl, optionally substituted C1-6 alkylsulfonamino, optionally substituted (C1-C6)alkylsulfinyl, optionally substituted C1-6 alkylcarbonylamino, optionally substituted hetero(C4-C10)aryl, hydroxyl, halogen, cyano, nitro, amino, formyl, and thiol; and - - - indicates an optional double bond. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9709886-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9383644-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9477150-B2 |
| priorityDate | 2005-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 509.