| abstract |
Compounds of formulas I-IV: (I), (II), (III) (IV), wherein: R 1 and R 4 -R 23 are independently selected from H and 1-3 carbon lower alkyl; and R 2 and R 3 are independently selected from H, 1-3 carbon lower O II alkyl, and —C—R a , wherein R a is 1-3 carbon lower alkyl. Pharmaceutical compositions, which include any of Compounds I-IV and a pharmaceutically acceptable carrier, methods of inducing tumor cell apoptosis by administering to a patient in need thereof an effective amount of any of Compounds I-IV, and methods for obtaining any of Compounds I-IV by extracting the compound from coral are also provided. |