| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9f70ad5899092adb520cf98c986aa5c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34485f111ffeb8444ae416461bf5a68e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fea72652b36324b0102f4f80321c59ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d9d7fdb1b2794380f36828871a3fdda
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c5f0289c73c4c32ece0d919f36c9ee35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_78ef72f0fe8c2996a9822fa791e681f0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_31f87c170ea6e478544c388bd11bb684 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-7716
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2201-0221
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-772
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-773
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6441 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-7703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0059
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-648
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-1455 |
| filingDate |
2007-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d263cfdfe3438b469e6087d66c558c3e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c37985dbe4fcf0164d11a6bc39d3697
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a4c9ec29a3d0528bb99216154839131
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d85a1e55d33d2f2db6494bd9039eda33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ad0232cac131482302b267312503d82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e87661e7a137fba66e2aa47d5321a9e |
| publicationDate |
2012-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8180421-B2 |
| titleOfInvention |
Resonance energy transfer based detection of nosocomial infection |
| abstract |
Disclosed herein are methods and devices for detection of hospital acquired infections. Disclosed methods may be utilized for continuous in vivo monitoring of a potential infection site or for periodic in vitro monitoring of tissue or fluid from a patient and may be utilized to alert patients and/or health care providers to the presence of a pathogen at an early stage of infection. Disclosed methods utilize fluorophore pairs that optically interact with one another according to Forster resonance energy transfer (FRET) or bioluminescence resonance energy transfer (BRET) mechanism. One member of the pair or a cofactor that interacts with an enzyme to form a member of the pair may be tethered to a device by a substrate that is specific for an enzyme expressed by a targeted pathogen. Upon interaction of the enzyme with the substrate, an optically detectable signal may be altered or initiated, detection of which may then provide information as to the existence of the pathogen at the site. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012268731-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9012830-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11284800-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11154198-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021259552-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11754488-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015037258-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11131619-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11676276-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9042967-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10438356-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11375898-B2 |
| priorityDate |
2007-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |