| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_00b272a9aba3bd7df40ad4753fd8ba3c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_75b765b53e6651e9863a3a35e4c1e164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_063fad0d002736c3875daaaf8af3fb64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5263824fbc201bf6eeba374259723630 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B15-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16C20-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-428
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-635
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-606
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-603
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-404
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B15-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-352
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-185
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4425
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-121 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N31-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06G7-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B15-30 |
| filingDate |
2009-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22856c838698100bb8c4c95cc87cadee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bedc010e106441a504e45ac00fe8546
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17cc9b715e1a3568f31fbc15e060dd7a |
| publicationDate |
2012-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8175860-B2 |
| titleOfInvention |
Method of inhibiting the growth of Helicobacter pylori |
| abstract |
A method of identifying a drug candidate to a target protein for inhibiting shikimate pathway comprising (a) performing a molecular program for computing a molecule conformation and orientation relative to an active site of the target protein and selecting top-rank molecules, (b) generating protein-molecule interacting profiles and identifying conserved interactions and pharmacophore spots, (c) developing homologous pharmacophore models for identifying pharmacophore hot spots, (d) rescoring molecules selected from step (a) by their homologous pharmacophore scores, (e) selecting potential molecules having the highest homologous pharmacophore scores, and (f) acquiring corresponding real compounds of the potential molecules selected from step (c) and identifying their inhibitory activity on the target protein by bioassay. |
| priorityDate |
2009-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |