http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8163700-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_81d0f29ec22b2955615175c01ff3eb77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f396347c392634f97a23211e7780fe41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_89e35a4e7329b6ed8ef7621829d74b2e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a59ecdeba650bc856c03b945ab56ac31 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70503 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 |
| filingDate | 2010-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb0c9865e3f35a46cdadb4d8f807a5cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b2ec7ca82b7169825f6e1721be0e2d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bbe26c3346d3079b95e54c5b39eeef3 |
| publicationDate | 2012-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8163700-B2 |
| titleOfInvention | Inhibitors of myelin-associated glycoprotein (MAG) activity for regulating neural growth and regeneration |
| abstract | The present invention relates generally to products, compositions and methods useful for promoting neural repair and regeneration. The products and compositions of this invention include myelin-associated glycoprotein (MAG) derivatives that are inhibitors of endogenous MAG (e.g., mutant MAG proteins) and Nogo Receptor (NgR) binding inhibitors that are peptides derived from MAG, Nogo and OMgp that can bind to NgR and block NgR signaling. Peptides that can bind and activate NgR signaling are also provided. Inhibitory MAG derivatives and NgR binding inhibitors are useful for blocking the inhibition of neural regeneration mediated by proteins such as MAG, Nogo and/or OMgp in the nervous system. These inhibitors are also useful for treating neural degeneration associated with injuries, disorders or diseases. |
| priorityDate | 2002-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 139.