Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c66f68e0bf9501e55a226e4f50521f14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01733884cc888894a4579e6d14f90508 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f484da65aefc8fbb0c90c9eece740b1d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-501 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-50 |
filingDate |
2010-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_889cc808908dfa452f2c00271401ed09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c853071f96a0f35288ead13512b38f88 |
publicationDate |
2012-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8153770-B1 |
titleOfInvention |
Mutants of human fibroblast growth factor having increased stability and/or mitogenic potency |
abstract |
Mutants of human FGF-1 are disclosed having increased stability and mitogenic potency. In the FGF-1 polypeptide, primarily residue 12 is substituted with cysteine and/or residue 134 is substituted cysteine, valine or threonine to render the polypeptide more stable and/or to increase its mitogenecity. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9957310-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9783587-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11103553-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10000540-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10385113-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11479590-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3666791-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11479591-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015148293-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11267855-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9469680-B2 |
priorityDate |
2007-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |