| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_45dd5f0c2a647782402455cdc565b395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b94046ca5c7f15896736d7ca6998dbbb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c76778a8b3a28686f1fdccd2c5f17f5 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-4006 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-685
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N57-26 |
| filingDate |
2006-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2012-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8d44de951ca119d1b2ec99b4bd649cb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0344bd7985fde05b084ff002bce62847
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81c48de2e6616e611782d9b9992bebf7 |
| publicationDate |
2012-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8153615-B2 |
| titleOfInvention |
Synthesis of glycerolipid carbamates and dicarbamates and their use as an antitumor compounds |
| abstract |
The syntheses and in vitro antitumor properties of carbamate-containing, dicarbamate-containing, and ureido-containing phospholipid compounds that have an ether linkage at the C-1 position of a glycerol backbone, a carbamate, dicarbamate, or ureido moiety at the C-2 position of the glycerol backbone, and a phosphocholine, phosphonocholine, or glycoside moiety at the C-3 position of the glycerol backbone are described. The synthesis and antiproliferative activity of ether lipids with a naphthol moiety at the C-1 position are also described. These compounds were shown to be potent inhibitors of cancer cell growth. These compounds are useful for killing cancer cells and treating cancer. |
| priorityDate |
2005-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |