http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8153392-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e25cd0155b6222599bd09b2e035c3421 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_762f2b0067b78fe75da745c27706bead |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-323 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 |
| filingDate | 2008-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e7f25a17a1acfa3bd9e3663d6cc857b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_212612ee4b62d02f752e8370540eecf6 |
| publicationDate | 2012-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-8153392-B2 |
| titleOfInvention | Method(s) of preventing, arresting, reversing and treatment of atherosclerosis |
| abstract | A method of detecting, diagnosing and prognosticating atherosclerosis by measuring the activities of Δ6 and Δ5 desaturases is described. It is suggested that enhancing the activities of Δ6 and Δ5 desaturases results in an increase in the plasma, leukocyte, platelet and endothelial cell levels of γ-linolenic, dihomo-γ-linolenic, arachidonic, stearidonic, 20:4 ω-3, eicosapentaneoic and docosahexaenoic acids and PGE1 (prostaglandin E1), prostacyclin (PGI2), prostaglandin I3 (PGI3), lipoxins, resolvins, protectins, nitric oxide, and nitrolipids that prevent, arrest and reverse atherosclerosis. The invention is also directed to the delivery of proteins, peptides, lipids, lipoproteins, glycolipids, statins and troglitazones and their derivatives, and other compounds (synthetic or natural), cDNA clones and genes of Δ6 and Δ5 desaturases to enhance the activities of Δ6 and Δ5 desaturases in vivo to prevent, arrest, reverse and treat atherosclerosis. |
| priorityDate | 2007-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1000.