http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8153376-B2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac23d8501102bd21ed7ede5b1d4e8e06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f1349f81b8b89dc6260b74a99365b48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4cf8c2b9ffbf051808a5eab3912ea716 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bbe675b46d686407d64e31a937562663 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-325 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2007-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2012-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f277ff539fffdaaf2e2fb84922647d41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ec6723d73c4392ca9518a8b8a8557ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b3fd688919a45cf67f5186f0be0adc8 |
publicationDate | 2012-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-8153376-B2 |
titleOfInvention | Means and methods for diagnosing and/or treating a subject at risk of developing heart failure |
abstract | The present invention relates to a method for identifying a subject at risk of developing heart failure, comprising: (a) determining the level of one or more biological markers in a biological sample of said subject; (b) comparing the level of said biological marker to a standard level of the same biological marker; and (C) determining whether the level of the marker is indicative of a risk for developing heart failure, wherein the biological marker is Krüppel Like Factor 15 (KLF-15) and/or lysosomal integral membrane protein-2 (LIMP-2) and/or fragments and/or variants thereof, and/or wherein the biological marker is a gene coding for KLF15 and/or LIMP-2, and/or fragments and/or variants thereof. The invention further relates to use of the KLF15 and/or LIMP-2 protein, and/or the gene coding for KLF15 and/or LIMP2, and/or fragments, and/or variants of said genes and/or proteins, for the preparation of a medicament for a prophylactic and/or a therapeutic medicament for prevention and/or treatment of heart failure. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012270244-A1 |
priorityDate | 2006-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 418.